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COLLAGEN · WHAT NOBODY EXPLAINS

I called it a subscription to a feeling. It turned out I'd run the test wrong.

For eighteen months I told anyone who'd listen that collagen was ground-up cow skin with a good label and a bad price. I was half right. Here's what I got wrong, what I checked before I paid, and the two things it never did for me.

*Dawn Reilly is a Mofu customer. She was paid for her time. Her words have been edited for length, not for content.

I want to start with what I used to say about this at dinner. Otherwise none of the rest is worth reading.

I thought it was hooey. I want to be accurate about how I said it, though, because I know how I sounded.

What I actually said, more than once, was that it was ground-up cow skin with a nice label on it. My sister-in-law Ashley brought it up at Thanksgiving and I said, out loud, in front of her kids: Ashley, you're drinking gelatin.

That wasn't kind. She has reminded me of it since.

And I want to be exact about what I believed, because it isn't the shape people assume. I didn't think it was a con. I thought the people selling it knew perfectly well it did nothing, and had found a legal way to say so.

Those are different accusations. Mine was the ruder one.

It's a subscription to a feeling.

I used that line for a year and a half. Mark(my husband) laughed the first time, and after that I kept using it, the way you do when you realise it actually works.

Then we moved my mother into her care home.

I'd packed her photo albums into a banker's box and I carried it in from the car. It's forty feet of flat sidewalk. Maybe fifty.

I put it down twice.

A kid who works there, twenty or so, came out and took it off me. He didn't ask. That's the part. He didn't say can I get that for you. He just took it, the way you take something off someone who shouldn't be carrying it.

My mother was in the chair by the door watching all of this. She's eighty-one. She said: let him, honey.

She said it in the voice she used when I was pregnant with Cole.

I put the box down. Twice. On a flat sidewalk.

It wasn't a photograph and it wasn't my face. It was that two people decided independently that I'm the one who gets helped now. One of them was my mother.

And I couldn't argue with either of them.

THE OBJECTION

"It's all amino acids at the end of the day." Half right.

My brother-in-law Ray reads a lot about supplements. He told me your body breaks any protein down into amino acids and then uses them wherever it wants. There's no label on the outside saying deliver to face.

He was right about that. I want that on the record.

What got me, eighteen months later, was that Mofu said the same thing Ray did. And said it first, before anything else. Your body breaks it down. Whole collagen and gelatin mostly go to waste. The sceptics have the science right.

Then it added the one thing Ray hadn't accounted for. Hydrolysed collagen is already partly broken down before you drink it, and some of the small pieces survive digestion and show up in human blood within a couple of hours.

Then it stopped.

That's the part that got me. It didn't go on to claim those pieces travel to my face. Somebody decided not to write the next sentence, and the next sentence would have sold more.

Ray was right that it gets broken down. He was wrong that broken down means gone. Those are two different claims, and in eighteen months of reading nobody had separated them for me.

What I could check

  • Intact collagen and gelatin are broken down in digestion and largely wasted.
  • Specific di- and tri-peptides survive digestion and are measurable in human blood within one to two hours.
  • The trials that found an effect used 2.5 to 10 grams a day.²⁻⁴

What I couldn't

  • That those peptides then travel to the skin in humans. That is where the evidence stops, and so do we.
  • That a larger dose does more. There is no dose-response evidence above roughly 5 grams.
  • That a lower molecular weight absorbs better. A manufacturer's own published study found it did not.⁵

Numbered sources at the foot of this page.

MOFU COLLAGEN PEPTIDES, UNFLAVOURED

One ingredient. 20g a scoop. The number is on the pack.

  • 20g of hydrolysed collagen peptides per serving, printed on the panel
  • One ingredient on the unflavoured: bovine hide collagen peptides
  • Dissolves in about five seconds in chilled water
See the twelve week supply

WHY THE LAST TUB DID NOTHING

Three ways this fails. Two of them were mine.

I didn't find out that collagen doesn't work. I found out that a few weeks at half a dose doesn't work.

  1. I stopped at week three.

    I bought the first tub the winter before all this. I'm not going to name it.

    I didn't finished that tub and stopped three weeks in. I know it was before Easter, because I remember thinking I'd have decent hands for Easter, and then never thinking about it again.

    The trials measure skin at eight to twelve weeks, and joints at twelve to twenty-four. Nobody told me that. So I invented my own number, and mine was shorter.

    I didn't think it was a scam. I thought it worked on other people.

  2. Then I halved the scoop, and said nothing about it for a year.

    Around the second week, I went to half a scoop. Nobody told me to. I looked at how fast the tub was going down, worked out what a year of that cost, and thought: I'll stretch it.

    A week later I concluded the experiment had failed.

    I've run payroll for eleven years. I know exactly what happens when you change the input and keep the report. I'd have caught it in four seconds on somebody else's spreadsheet. It took me the best part of eighteen months to catch it in my own life, and I think that's because I didn't believe I was running an experiment. I thought I was buying a product that either worked or didn't.

    I thought I was the failed variable. Not the product. Me.

  3. The third one wasn't mine. It's the most common of the three.

    A large share of what's sold as collagen is a gummy or a drink measuring its dose in milligrams. Five to twenty-five times below anything that has ever been studied.

    That wasn't my mistake, but only because I happened to buy a powder. The label answers it in about four seconds, which is roughly four seconds longer than most of us spend on it.

    Check the panel of the last one you bought. The number is the whole story.

WHY IT ALL WENT AT ONCE

It only felt sudden

I looked things up constantly. Almost always after ten at night, which tells you something.

Reddit, mostly. The menopause boards. I'd never opened Reddit in my life until all this started. I now know more about my own endocrine system than the physician's assistant who told me my bloodwork was normal and asked whether I'd considered that I might be stressed.

Here's the part nobody had put in front of me. Estrogen helps regulate collagen production in skin and connective tissue, and it falls during the menopause transition.⁶

One reason, not four. Somebody should have sat me down at forty and said so. Instead I found it on a message board at eleven at night, from a stranger, about eighteen months after I needed it.

WHAT I CHECKED FIRST

I'm a payroll administrator. Of course I read the panel.

Ingredients: bovine hide collagen peptides. That was the list. I read it three times because I assumed I'd missed a page.

That mattered to me more than anything else on the site, for a reason that isn't obvious. When I took the other one I broke out along my jaw around week five. I stopped, started again, and never worked out whether it was the collagen, the flavouring, or nothing at all.

With one ingredient there's nothing else to blame. If it does something to me, I know what did it. If it does nothing, I know what didn't.

20g Hydrolysed collagen peptides per serving
1 Ingredient, on the unflavoured
18g Protein per serving
70 Calories per serving

COMPLETE INGREDIENT LIST Bovine hide collagen peptides. That is the whole list.

THE LINE THAT ACTUALLY MOVED ME

Twenty grams a scoop, on the panel and in the advertisement as well, which the other one wasn't.

Then this: the trials that actually found something used two and a half to ten grams a day, and there's no evidence that more is better.²⁻⁴

That's a company telling me I can probably use half of what it would like to sell me. I read that twice. I'm not a soft touch and I don't get moved by advertising, and that moved me, because nobody puts that on a page by accident.

SAME DOSE, TWO WAYS IN

Unflavoured if you would rather taste nothing. Chocolate if the last one put you off.

  • The grams are printed on the panel, not just in the ad
  • Dairy free, no added sugar in the chocolate
  • Same 20g dose in both flavours, so there is no decision to make
See both

PUBLISHED IN ADVANCE

Most people quit after a few weeks. The trials measure at week twelve.

This is the chart I didn't have the first time. It says when to look, not what you'll find. It's also the only reason I didn't quit a second time.

  1. Weeks 1 to 2

    Nails, then hair

    What people most often report noticing first, and the reason the rest is worth waiting for.

    Commonly reported by users. Not a trial endpoint, and not a promise.

  2. Weeks 2 to 4

    Skin

    The window the trials measure in. Judging it at week four is judging it early.

  3. Weeks 4 to 12

    Joints

    The longest of the three. Described by sound more often than by feel.

When to look, not a statement of what you will find. Individual experience varies.

ONE PERSON'S TWELVE WEEKS

What happened to me, with the dates I wrote down

I have dates because I put them in my phone. I'd like to say that was rigour. It wasn't. I'd decided in advance that I would quit again at week nine, and I wanted to catch myself doing it.

I started, and I wrote the date down.

Nails first, and fast. There's a note in my phone from about few days in that just says: nails ???

By week three there were no question marks. I'd had to start cutting them again, which I hadn't had to do in years.

That is not a feeling. That is a nail clipper.

That's what bought them the next two months. I had something to point at while the rest of it hadn't happened yet.

Hair, somewhere around week two. I noticed it in the drain, which is a grim way to measure anything and the most honest measurement I've got. There was less of it.

Skin I want to be careful about, because I know I wanted this one. Around week four my face felt different in the mornings. Less like it needed something immediately. I don't fully trust that, because I'd been waiting for it since the day I started. If you ask me to point at what changed, I can't. The only fact I can give you is that I stopped using the heavy cream around week twelve and never went back to it.

The joints are the one I'd put in the article.

We have a staircase in this house that had announced me for years. Every riser, the same knee. Mark used to know what floor I was on.

Week five or six, I came down them and they were quiet. I stopped on the bottom step. Then I went back up and came down again, to check.

I did that twice. Half six in the morning, going up and down my own stairs like an idiot. That's the moment I stopped treating this as something I was trying.

THE ARITHMETIC

I built a sheet. That's not a joke, it's just what I do with a decision.

Fourteen servings a tub. One a day is a fortnight. Twelve weeks is six tubs. A full year at a full scoop is twenty-six tubs, and I wrote that number down and sat looking at it for a while, because it's a real number and it isn't a small one.

One tub14 servings at one 20g scoop a day
2 weeks
A fair test of this productThe trials measure skin at 8 to 12 weeks
6 tubs
One year, at a full scoopThe number I wrote down and sat looking at
≈26 tubs
Twelve week supply (2 tubs every month)Subscription Price
$50.40 each
One month supply (2 tubs)One time Purchase
$56.00 each
Use my code: DAWN20 for $20* off your first orderOnly for one time purchases
DAWN20

My conclusion was that twelve weeks costs a number I could say out loud without flinching, and that I'd never once actually run this test properly, so I didn't know what I thought I knew. And to get you guys started, I partnered with MOFU for a discount code. Remember to use it.

If you're standing where I was a year ago, I'd say three things.

The first is that it wasn't your fault. There's a reason your skin and your hair and your knees all shifted inside the same few months, and it isn't that you let yourself go. Nobody sat me down at forty and explained any of it, and I'd want you angry at the right thing. I spent two years angry at myself, and that cost me a lot more than a tub.

The second is about the test. You didn't find out that collagen doesn't work. You found out that a few weeks at a low dose doesn't work, and you've been living off the wrong finding ever since. Nobody gave you the conditions, so you made some up, and then you believed your own bad experiment for a year and a half.

The third is small, and it's the one I'd actually lead with. Don't check the mirror. You'll cheat. We all cheat. You'll stand at a certain angle in a certain light and talk yourself into something or out of it, and either way you'll have learned nothing.

Check the stairs. Check the jar lid. Check whether you're still cutting your nails three months from now.

The mirror will lie to you. The staircase has no opinion.

THE TWELVE WEEK SUPPLY

Twelve weeks of a habit you already have every morning.

  • Send back an opened tub. No empty bottle to keep.
  • Cancel in one click. No phone call.
  • The annual cost is on this page, above.
Start the twelve weeks

This is an advertisement and not an actual news article, blog, or consumer protection update.

*Dawn's experience. Individual results and timelines vary.

† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

If you have a history of kidney stones or kidney disease, speak to your doctor before taking a collagen supplement. Speak to your doctor before starting any supplement if you are pregnant, breastfeeding or taking medication.

SOURCES

  1. Iwai K, Hasegawa T, Taguchi Y, et al. Identification of food-derived collagen peptides in human blood after oral ingestion of gelatin hydrolysates. J Agric Food Chem. 2005;53(16):6531-6536. Peptide-bound hydroxyproline peaked in plasma 1 to 2 hours after ingestion; Pro-Hyp was the major constituent.
  2. Proksch E, Segger D, Degwert J, Schunck M, Zague V, Oesser S. Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology: a double-blind, placebo-controlled study. Skin Pharmacol Physiol. 2014;27(1):47-55. 69 women aged 35 to 55, 2.5 g or 5 g daily, measured at 8 weeks.
  3. Clark KL, Sebastianelli W, Flechsenhar KR, et al. 12-week study on the use of collagen hydrolysate as a dietary supplement in athletes with activity-related joint pain. Curr Med Res Opin. 2008;24(5):1485-1496. 147 subjects, 10 g daily, 12 weeks.
  4. Zdzieblik D, Oesser S, Gollhofer A, Konig D. Improvement of activity-related knee joint discomfort following supplementation of specific collagen peptides. Appl Physiol Nutr Metab. 2017;42(6):588-595. 139 subjects, 5 g daily, 12 weeks.
  5. Virgilio N, Schon C, Modinger Y, et al. Absorption of bioactive peptides following collagen hydrolysate intake: a randomized, double-blind crossover study in healthy individuals. Front Nutr. 2024;11:1416643. Compared bovine collagen hydrolysate at 2,000 and 5,000 Da; molecular weight did not affect bioavailability of the peptides measured. Funded by Rousselot BV, a collagen manufacturer, with five of the nine authors employed by the company.
  6. Thornton MJ. Estrogens and aging skin. Dermatoendocrinol. 2013;5(2):264-270. Review of estrogen's role in dermal collagen and the effect of its decline at menopause.